Development and Optimization of Acyclovir Loaded Mucoadhesive Microspheres by Box – Behnken Design
نویسندگان
چکیده
منابع مشابه
Design and Development of Mucoadhesive Acyclovir Tablet
The purpose of this study was to design and optimize an oral controlled release acyclovir mucoadhesive tablet, in term of its drug release and mucoadhesive strength. A 32 full factorial design was employed to study the effect of independent variables like Carbopol-934P and hydroxypropyl methylcellulose K100M, which significantly influence characteristics like swelling index, ex-vivo mucoadhesiv...
متن کاملDesign and Development of Mucoadhesive Acyclovir Tablet
The purpose of this study was to design and optimize an oral controlled release acyclovir mucoadhesive tablet, in term of its drug release and mucoadhesive strength. A 32 full factorial design was employed to study the effect of independent variables like Carbopol-934P and hydroxypropyl methylcellulose K100M, which significantly influence characteristics like swelling index, ex-vivo mucoadhesiv...
متن کاملFormulation and Optimization of Oral Mucoadhesive Patches of Myrtus Communis by Box Behnken Design
Purpose: Recurrent aphthous stomatitis (RAS) is the most common painful ulcerative disease of oral mucosa happening in ~20% of people. Aimed to develop Myrtus communis L. (Myrtle) containing oral patches, we applied box-behnken design to evaluate the effect of polymers such as Polyvinyl pyrrolidone (PVP), Gelatin, Methylcellulose (MC) and Pectin. Methods: The patches properties such as tensile ...
متن کاملdesign and development of mucoadhesive acyclovir tablet
the purpose of this study was to design and optimize an oral controlled release acyclovir mucoadhesive tablet, in term of its drug release and mucoadhesive strength. a 32 full factorial design was employed to study the effect of independent variables like carbopol-934p and hydroxypropyl methylcellulose k100m, which significantly influence characteristics like swelling index, ex-vivo mucoadhesiv...
متن کاملDesulfurization of coal by HNO3 leaching: Optimization of influential factors using Box-Behnken design
Sulfur is one of the most significant impurities in coal, which reduces the quality of coal and also results in environmental pollution. This work was aimed to investigate the removal of sulfur from coal by the leaching method employing parameters expected to affect the removal rate such as acid concentration (10-30%), temperature (40-80 °C), and reaction time (40-100 min). A response surface m...
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ژورنال
عنوان ژورنال: Dhaka University Journal of Pharmaceutical Sciences
سال: 2019
ISSN: 1816-1839,1816-1820
DOI: 10.3329/dujps.v18i1.41421